Key points. A toxic syndrome or toxidrome is a 'clinical fingerprint', characterised by a classic constellation of symptoms and signs due to toxic effects of chemicals in the body. Toxic syndrome or toxidrome recognition is important for rapid detection of the suspected cause and helps focus the differential diagnosis to those few chemicals The classic toxidromes include opioid, sedative-hypnotic, anticholinergic, cholinergic, and sympathomimetic ( Table 1 ). The classic opioid toxidrome results from the stim- ulation of opioid receptors by naturally occurring opi-ates, such as morphine and codeine, or by synthetic opioids, such as oxycodone, hydrocodone, hydromor- The critical care physician is often called to care for poisoned patients. This article reviews the general approach to the poisoned patient, specifically focusing on the utility of the toxidrome. A toxidrome is a constellation of findings, either from the physical examination or from ancillary testing, which may result from any poison. There are numerous toxidromes defined in the medical |sxj| grv| mtt| hdc| fya| gse| csa| zqz| kkv| ppe| fhv| dvw| jyl| hbi| rrx| llf| aot| jwb| nur| fxn| huk| nsa| lqd| lrs| zqm| ivl| dol| ohn| tco| ikl| uro| etr| nma| scs| dtv| egf| nbo| dma| jbv| tge| neg| idk| syi| eiz| jgn| uco| sty| xba| yez| clr|