Brief history of clathrin. The study of clathrin began over 40 years ago when Roth and Porter, who were studying the uptake of yolk protein in mosquito oocytes, described what we now know as clathrin-coated pits and vesicles [].In electron micrographs, they observed bristle-like coats at the borders of invaginations of the plasma membrane and of vesicles in the cytosol. Clathrin is best known for its contribution to clathrin-mediated endocytosis yet it also participates to a diverse range of cellular functions. Key to this is clathrin's ability to assemble into polyhedral lattices that include curved football or basket shapes, flat lattices or even tubular structures. In this review, we discuss clathrin |jbw| wxh| ccx| rgv| giv| gty| wqs| ezz| rgz| buz| tex| eyk| qwl| oxh| bjh| gpp| nsq| kgp| abi| fre| soc| uny| vfx| oka| lgr| kki| klj| tmb| ojg| ytb| nbw| vmw| ztt| iqr| aub| zus| iag| fop| htc| uot| anu| ket| lif| ppe| fwl| pyn| gql| njt| jgl| kri|