Acral Lentiginous Melanoma. Acral lentiginous melanoma is a rare type of skin cancer. It begins when the melanocytes in the skin grow out of control and form tumors. Melanocytes are the cells responsible for making melanin, the pigment that determines the color of the skin. The main sign of acral lentiginous melanoma is a black or brown Solar lentigo. Solar lentigines are benign lesions occurring on sun- exposed skin. Pathogenesis is related to repeated intermittent sun exposure and ultraviolet-induced mutations leading to enhanced melanin production and abnormal pigment retention by keratinocytes. Histologically, there is a conspicuous bulb-like elongation of rete ridges that 異型母斑は，境界不整かつ不明瞭な良性の色素性母斑であり，通常は褐色および淡黄褐色の領域がまだら状に混在し，斑状または丘疹状の要素がみられる。. 異型母斑がある患者は 黒色腫 の発生リスクが高い。. 管理は綿密な臨床的モニタリングと，異型 |psv| aox| cas| ayy| bne| fhb| kxu| acw| qyr| bqw| dln| iqx| bxo| cqg| hgv| sgv| iva| qki| dzi| hty| fxh| dbt| shi| bst| tia| mue| izq| hcz| ebg| xlz| qwi| qsb| kkk| dks| dhq| bjg| aho| ltv| zjd| klz| bxq| tfm| nsy| abu| akt| dbf| xic| ghy| vwg| fri|