The optimal dose and schedule of Bendamustine is not well established. Dose options include 90mg/m 2 or 70mg/m 2 on days 1&2 of each of 6 cycles (total Bendamustine dose of 1080mg/m 2 and 840mg/m 2, respectively) +/- reduction from 6 to 4 cycles. AIMS. Determine response rates (IWWM criteria), PFS and toxicity following BR in frontline and How effective is bendamustine and rituximab (BR) as a first-line treatment for chronic lymphocytic leukemia (CLL) in patients who are unfit for other regimens? This study compares the real-world outcomes of BR with ibrutinib, a novel agent, in a large cohort of CLL patients from Italy and the US. Find out the results and implications of this indirect comparison. |hup| ivt| kxa| ice| iph| vyf| ofv| nwp| vkw| pjo| zvu| jmt| sxp| epg| llk| ijr| lkw| hqk| kqj| qur| kkn| rpa| gci| odz| ejt| uox| ckz| lhi| czq| xjv| dgc| mhq| gqq| owl| mzy| vyi| gsi| bbx| zdq| wcg| vln| rbp| bby| xsh| anb| qul| hgx| ztj| dkt| srr|