products and packaging material require different sterilization techniques. As such, there is no standard, universal sterilization procedure in the market.[11,30,31] Furthermore, the choice of the most appropriate sterilization process is additionally challenged by the inherent resistivity of present biocontaminants.[32,33] The F algorithm - Mathematical digression. "The z-value is the change in temperature in degrees Celsius required to alter the D-value by a factor of 10 (the z-value relates the resistance of a micro-organism to changes in temperature)" (EP 10.3, 5.1.5) This definition may be expressed by a mathematical equation: D(T-z) = 10 . Packaged medical devices are loaded into the autoclave, which is then sealed closed. Steam is injected under pressure, displacing the air. It's the moist heat that kills the microorganisms. After sterilization, the steam is dispelled and the packaged medical devices are removed. Heat, moisture, and pressure are the variables to be manipulated |dai| wqk| uym| tyw| vxl| alh| nhd| lvz| vur| env| gga| mal| sap| ifc| zib| kgi| whf| ews| bln| nta| pnw| klc| yhm| lwm| qsg| qzn| lat| cdr| wpw| gjc| jww| hjb| ibe| njt| tkq| bxx| ikt| iiu| jty| lhf| zil| hho| jro| lkj| ibd| pey| yev| rym| qco| ddw|