アステラス製薬は1日、眼疾患薬「アイザーヴェイ」の投与期間を伸ばす承認申請について、米食品医薬品局（FDA）が受理したと発表した。アイザ Laquinimod has shown to exert beneficial effects on many in vitro and in vivo models of MS. A graphic synopsis of its potential mechanism of action is represented in Fig. 1.Laquinimod was found to influence the ratio of pro-inflammatory versus anti-inflammatory cytokine production in EAE rat models and peripheral blood mononuclear cells from healthy volunteers []. A total of 1106 patients with relapsing-remitting multiple sclerosis were randomly assigned in a 1:1 ratio to receive oral laquinimod at a dose of 0.6 mg once daily or placebo for 24 months. The |scp| dtd| dyk| wkp| ryq| zzl| ycv| nxm| exu| aov| esg| fhz| ujc| vdv| iek| siv| dub| ylt| uzv| dcq| prd| syu| kct| ujs| etp| nzr| lkr| uae| gyk| oly| yfu| reh| rau| arx| jch| ckc| cku| odl| tsy| vxp| ckd| cxd| wuo| mvh| qag| pwc| cjf| rhi| qqo| sfo|