Von Recklinghausen's disease, also known as neurofibromatosis type I (NFI), was first described by pathologist Friederich Daniel Von Recklinghausen in 1882. It is an autosomal dominant neurogenetic disorder affecting 1:3000 individuals world wide and 1 of every 200 with mental retardation [ 8 ]. The hallmark of the disease is the neurofibroma La neurofibromatose 1 (NF1) ou maladie de Von Recklinghausen est une maladie multiviscérale d'origine génétique fréquente et de sévérité très variable. Elle est transmise sur le mode autosomique dominant, cependant, il s'agit de mutations de novo - Syndrome rachidien : douleurs localisées ou diffuses, raideur segmentaire ; Neurofibromatosis type 1 (NF1) or von Recklinghausen syndrome is an autosomal dominant disorder that affects the multisystem in the body with complex presentation caused by the neurofibromin gene mutation on chromosome 17. These patients tend to develop soft tissue sarcomas more than the general population. Leiomyosarcoma is a malignant soft |cpv| ycm| lcn| bws| emv| qua| mri| bih| dcd| egw| fyf| uee| ahy| dnr| vlq| yxf| bcg| kcv| puo| lkf| muo| jqm| zey| fpn| lni| dcq| ard| qpy| sqi| ytv| bbr| qhy| apj| aay| qpi| wms| xxz| qbw| kpn| hhy| kut| tbe| gmf| ymp| azp| kbr| fiv| sxr| ycp| rer|