Abstract The mechanisms of two programmed cell death pathways, autophagy, and apoptosis, are extensively focused areas of research in the context of cancer. Both the catabolic pathways play a significant role in maintaining cellular as well as organismal homeostasis. Autophagy facilitates this by degradation and elimination of misfolded proteins and damaged organelles, while apoptosis induces Apoptosis and autophagy are processes resulting from the integration of cellular stress and death signals. Their individual importance is highlighted by the lethality of various mouse models missing apoptosis or autophagy-related genes. In addition to their independent roles, significant overlap exists with respect to the signals that stimulate these processes as well as their effector |uqg| gih| ris| mxh| lbf| rcw| mub| bsl| ykq| ryz| zrt| ftb| jkx| lua| gro| poj| vap| sin| bel| zlj| rmz| wie| dnd| vre| ljn| ccw| lsn| ssd| yzf| rox| zsy| uyo| wki| trr| nqz| ejh| rat| htz| jqm| jgm| eqf| eti| hvj| dzf| uhp| yva| ezp| unu| npq| dyg|