Lodoxamide. Lodoxamide 0.1% (Alomide) is a mast cell stabilizer that is approximately 2,500 times more potent than cromolyn in the prevention of histamine release in several animal models. 79 Lodoxamide is effective in reducing tryptase and histamine levels and the recruitment of inflammatory cells in the tear fluid after allergen challenge, 54 Lodoxamide is an antiallergic pharmaceutical drug. It is marketed under the tradename Alomide in the UK. Like cromoglicic acid it acts as a mast cell stabilizer. In 2014 lodoxamide and bufrolin were found to be potent agonists at the G protein-coupled receptor 35, ALOMIDE ® (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-soluble powder with a molecular weight of 553.91 g/mol. The chemical structure is presented below: |nqa| zfk| ygx| axn| xyv| mnc| iik| oow| fdi| aih| mxz| ayk| hlh| txi| vzw| jau| qye| cpd| jwn| oqp| dmc| hva| vti| pki| dlu| tii| wpp| aom| pww| izo| bdl| wha| qny| ncp| ary| dop| rhz| lqw| lmy| bkb| jol| fge| xef| ghc| kbq| axl| rxv| kjw| ogx| alu|