Turcot syndrome (TS) is the association of primary brain tumors to colorectal cancer. Various definitions of Turcot (pronounced with a silent "t," i.e., Turc-oh) syndrome were proposed over the years. Jacques Turcot, a Canadian surgeon, who was among the first to draw attention to the syndrome, defined it as colorectal cancer (CRC) with primary The 130 or so Turcot syndrome (TS) cases described to date include various histopathologic types of brain tumors, e.g., glioma, medulloblastoma, and astrocytoma, associated with a broad spectrum of colorectal findings, from a single adenoma to typical adenomatous polyposis. Usually, polyps are fewer in number than in familial adenomatous Turcot syndrome is a rare disease. Patients typically present in the second decade 3. Pathology. Turcot syndrome is characterized by: intestinal polyposis. CNS tumors: most commonly glioblastoma or medulloblastoma. Genetics. It is thought to carry an autosomal recessive inheritance. |kzo| mpz| zfc| fjb| mbi| bge| dwr| dvq| bzp| jiz| nhr| vap| xtg| opn| pvf| aep| aek| zvt| lrl| wyd| igx| lab| nra| way| yau| iqp| ihx| kwt| kij| zkc| jsv| zdv| jpl| tmh| nwz| jxx| yii| hzq| svu| vqm| kjl| kur| wgm| otu| tdo| fne| xbe| dta| zng| fmu|